DHEA is a precursor to both estrogen and testosterone. It has been proposed as a treatment for heart disease, diabetes, high cholesterol, obesity, Alzheimer's disease, memory loss, fatigue, osteoporosis, and HIV. Complementary Cancer Therapies by Dan Labriola ND, page 192

Besides helping to maintain proper neurological function, DHEA appears to have a very broad range of positive effects. It is widely believed that DHEA slows the biological symptoms of aging, and helps protect the body from cancer, diabetes, arthritis, osteoporosis, obesity, viral and bacterial infection, and hypertension. Therefore it is understandable that many researchers regard DHEA as a "wonder drug."
Brain Longevity by Dharma Singh Khalsa M.D. with Cameron Stauth, page 402

Whenever doctors talk about the safety of a medicine they separate it into short-term safety over a few days or weeks, and long-term safety over months and years of use. Dr. Nestler, a researcher at the Medical College of Virginia/ Virginia Commonwealth University in Richmond, gave 1600 mg of DHEA a day for 4 weeks to healthy young men without any serious side effects. At this dosage there was a lowering of cholesterol and a decrease in body fat, with a greater response in obese individuals. Most DHEA supplements on the market are less than 50 mg.
DHEA by Ray Sahelian MD, page 9

Dehydroepiandrosterone (DHEA) is a steroid hormone chemically related to testosterone and estrogen. It is made by the adrenal glands from cholesterol. DHEA levels in the human body peak in the mid-20s and steadily decline beginning about the mid-30s. Researchers have studied the actions of DHEA for over 20 years and have found that it may have beneficial implications in many areas, such as improving immunity; reducing meno-pausal symptoms; preventing cancer, heart disease, Alzheimer's disease, and chronic inflammation; improving longevity; and aiding weight loss. DHEA should only be taken under the supervision of a physician who can monitor blood levels of steroids and cholesterol and existing health conditions. DHEA is contraindicated in both men and women who have hormone-related cancer.
Disease Prevention And Treatment by Life Extension Foundation, page 793

In fact, the benefits of DHEA supplementation may extend well beyond an anti-aging effect. Over the last decade, a number of studies have demonstrated that declining levels of DHEA are linked to such conditions as diabetes, obesity, elevated cholesterol levels, heart disease, arthritis, and autoimmune diseases. In addition, DHEA shows promise in enhancing memory and improving mental function in the elderly as well as increasing muscle strength and lean body mass, activating immune function, and enhancing the quality of life in aging men and women. Further research will be required to determine whether DHEA supplementation will be a useful therapy in all of these conditions.

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