Health Notice
By Martin Hickman, Consumer Affairs Correspondent
Published: 27 May 2007



Dear Parents,

I don't normally pass on the information I read on scientific studies, but this warrants our awareness.  As parents of adolescents who typically consume large amounts of the stuff, I thought you might want to know that we should keep our ears to the ground, so-to-speak, concerning many soft drinks.

Sodium Benzoate used as a preservative in foods - NOTE: This is a first study and we can never base wide-sweeping decisions on one study.  However, this concern has been raised many times in the past, and now there seems to be some evidence to support earlier fears.  The chemistry presented here is sound and the link between mitochondrial damage and a (growing) variety of diseases is also correct.  We need to watch as more studies are performed.  I'm not sure that I will change any habits yet, but I will inform my family and we will watch for more evidence. (...we LOVE our Dr. Pepper.)

Caution: Some soft drinks may seriously harm your health  
Expert links additive to cell damage

A new health scare erupted over soft drinks last night amid evidence they may cause serious cell damage. Research from a British university suggests a common preservative found in drinks such as Fanta and Pepsi Max has the ability to switch off vital parts of DNA.

The problem - more usually associated with ageing and alcohol abuse - can eventually lead to cirrhosis of the liver and degenerative diseases such as Parkinson's.

The findings could have serious consequences for the hundreds of millions of people worldwide who consume fizzy drinks. They will also intensify the controversy about food additives, which have been linked to hyperactivity in children.

Concerns centre on the safety of E211, known as sodium benzoate, a preservative used for decades by the global carbonated drinks industry. Sodium benzoate derives from benzoic acid. It occurs naturally in berries, but is used in large quantities to prevent mould in soft drinks such as Sprite, Oasis and Dr Pepper. It is also added to pickles and sauces.

Sodium benzoate has already been the subject of concern about cancer because when mixed with the additive vitamin C in soft drinks, it causes benzene, a carcinogenic substance. A Food Standards Agency survey of benzene in drinks last year found high levels in four brands which were removed from sale.

Now, an expert in ageing at Sheffield University, who has been working on sodium benzoate since publishing a research paper in 1999, has decided to speak out about another danger. Professor Peter Piper, a professor of molecular biology and biotechnology, tested the impact of sodium benzoate on living yeast cells in his laboratory. What he found alarmed him: the benzoate was damaging an important area of DNA in the "power station" of cells known as the mitochondria.

He told The Independent on Sunday: "These chemicals have the ability to cause severe damage to DNA in the mitochondria to the point that they totally inactivate it: they knock it out altogether.

"The mitochondria consumes the oxygen to give you energy and if you damage it - as happens in a number of diseased states - then the cell starts to malfunction very seriously. And there is a whole array of diseases that are now being tied to damage to this DNA - Parkinson's and quite a lot of neuro-degenerative diseases, but above all the whole process of ageing."

The Food Standards Agency (FSA) backs the use of sodium benzoate in the UK and it has been approved by the European Union but last night, MPs called for it to investigate urgently.

Norman Baker, the Liberal Democrat chair of Parliament's all-party environment group said: "Many additives are relatively new and their long-term impact cannot be certain. This preservative clearly needs to be investigated further by the FSA."

A review of sodium benzoate by the World Health Organisation in 2000* concluded that it was safe, but it noted that the available science supporting its safety was "limited".

Professor Piper, whose work has been funded by a government research council, said tests conducted by the US Food and Drug Administration were out of date.

"The food industry will say these compounds have been tested and they are complete safe," he said. "By the criteria of modern safety testing, the safety tests were inadequate. Like all things, safety testing moves forward and you can conduct a much more rigorous safety test than you could 50 years ago."

He advised parents to think carefully about buying drinks with preservatives until the quantities in products were proved safe by new tests. "My concern is for children who are drinking large amounts," he said.

Coca-Cola and Britvic's Pepsi Max and Diet Pepsi all contain sodium benzoate. Their makers and the British Soft Drinks Association said they entrusted the safety of additives to the Government.


I checked, and yes, Dr. Pepper does contain the combination of sodium benzoate and vitamin C (ascorbic acid). I found the complete ingredient listings online at     http://www.bevnet.com/   where beverages are listed alphabeticaly under the "Reviews" tab.  Atomic X and SoBe beverages do not contain sodium benzoate. IBC and A&W Root Beers were not listed. (I did not check any others, because they are generally not part of our household drink inventory.)

References -
* the report referenced in this article http://www.inchem.org/documents/cicads/cicads/cicad26.htm#PartNumber:7
2-15-07 article
http://www.beveragedaily.com/news/ng.asp?n=65840-soft-drinks-fda-benzene
2-27-06 article      
http://www.beveragedaily.com/news/ng.asp?n=66084-benzene-soft-drinks-aba
3-6-07 article
http://www.foodnavigator-usa.com/news/ng.asp?n=66223-benzene-soft-drinks-fda
3-29-06 FDA's response
http://www.foodqualitynews.com/news/ng.asp?n=66727-fda-benzene-soft-drinks


Caution: Some soft drinks may seriously harm your health
Expert links additive to cell damage
By Martin Hickman, Consumer Affairs Correspondent
Published: 27 May 2007

A new health scare erupted over soft drinks last night amid evidence they may cause serious cell damage. Research from a British university suggests a common preservative found in drinks such as Fanta and Pepsi Max has the ability to switch off vital parts of DNA.

The problem - more usually associated with ageing and alcohol abuse - can eventually lead to cirrhosis of the liver and degenerative diseases such as Parkinson's.

The findings could have serious consequences for the hundreds of millions of people worldwide who consume fizzy drinks. They will also intensify the controversy about food additives, which have been linked to hyperactivity in children.

Concerns centre on the safety of E211, known as sodium benzoate, a preservative used for decades by the £74bn global carbonated drinks industry. Sodium benzoate derives from benzoic acid. It occurs naturally in berries, but is used in large quantities to prevent mould in soft drinks such as Sprite, Oasis and Dr Pepper. It is also added to pickles and sauces.

Sodium benzoate has already been the subject of concern about cancer because when mixed with the additive vitamin C in soft drinks, it causes benzene, a carcinogenic substance. A Food Standards Agency survey of benzene in drinks last year found high levels in four brands which were removed from sale.

Now, an expert in ageing at Sheffield University, who has been working on sodium benzoate since publishing a research paper in 1999, has decided to speak out about another danger. Professor Peter Piper, a professor of molecular biology and biotechnology, tested the impact of sodium benzoate on living yeast cells in his laboratory. What he found alarmed him: the benzoate was damaging an important area of DNA in the "power station" of cells known as the mitochondria.

He told The Independent on Sunday: "These chemicals have the ability to cause severe damage to DNA in the mitochondria to the point that they totally inactivate it: they knock it out altogether.

"The mitochondria consumes the oxygen to give you energy and if you damage it - as happens in a number if diseased states - then the cell starts to malfunction very seriously. And there is a whole array of diseases that are now being tied to damage to this DNA - Parkinson's and quite a lot of neuro-degenerative diseases, but above all the whole process of ageing."

The Food Standards Agency (FSA) backs the use of sodium benzoate in the UK and it has been approved by the European Union but last night, MPs called for it to investigate urgently.

Norman Baker, the Liberal Democrat chair of Parliament's all-party environment group said: "Many additives are relatively new and their long-term impact cannot be certain. This preservative clearly needs to be investigated further by the FSA."

A review of sodium benzoate by the World Health Organisation in 2000 concluded that it was safe, but it noted that the available science supporting its safety was "limited".

Professor Piper, whose work has been funded by a government research council, said tests conducted by the US Food and Drug Administration were out of date.

"The food industry will say these compounds have been tested and they are complete safe," he said. "By the criteria of modern safety testing, the safety tests were inadequate. Like all things, safety testing moves forward and you can conduct a much more rigorous safety test than you could 50 years ago."

He advised parents to think carefully about buying drinks with preservatives until the quantities in products were proved safe by new tests. "My concern is for children who are drinking large amounts," he said.

Coca-Cola and Britvic's Pepsi Max and Diet Pepsi all contain sodium benzoate. Their makers and the British Soft Drinks Association said they entrusted the safety of additives to the Government.



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